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2 OMIM references -
1 associated gene
10 signs/symptoms
PROTEIN INTERACTIONS: 1
3 OMIM references -
3 associated genes
No signs/symptoms info
Fibronectin glomerulopathy
Hereditary cerebral cavernous malformation

FN1 CCM2
KRIT1
PDCD10


INTERACTOME
ASSOCIATIONS

(click on a score value to see the evidence)
FN1
(0.72)
PDCD10



Citations in the biomedical literature:


Fibronectin glomerulopathy
FN1
Hereditary cerebral cavernous malformation
CCM2 KRIT1 PDCD10



Fibronectin glomerulopathy
Hereditary cerebral cavernous malformation

Synonym(s):
- GFND
- Glomerulopathy with fibronectin deposits

Synonym(s):
- Familial brain cavernous angioma
- Familial brain cavernous hemangioma
- Familial cerebral cavernoma
- Familial cerebral cavernous malformation
- Hereditary brain cavernous angioma
- Hereditary brain cavernous hemangioma
- Hereditary cerebral cavernoma

Classification (Orphanet):
- Rare genetic disease
- Rare renal disease
Classification (Orphanet):
- Rare circulatory system disease
- Rare developmental defect during embryogenesis
- Rare genetic disease
- Rare neurologic disease

Classification (ICD10):
- Diseases of the genitourinary system -
Classification (ICD10):
- Congenital malformations, deformations and chromosomal abnormalities -

Epidemiological data:
Class of prevalence: <1 / 1 000 000
Average age onset: variable
Average age of death: -
Type of inheritance: autosomal dominant
Epidemiological data:
Class of prevalence: 1-5 / 10 000
Average age onset: variable
Average age of death: normal
Type of inheritance: autosomal dominant

External references:
2 OMIM references -
No MeSH references
External references:
3 OMIM references -
No MeSH references

Fibronectin glomerulopathy

Very frequent
- Autosomal dominant inheritance
- Chronic arterial hypertension
- Edema of the legs / lower limbs
- Functional anomalies of the kidney and the urinary tract
- Hematuria / microhematuria
- Nephrotic syndrome
- Proteinuria
- Renal failure
- Renal glomerular defect / glomerulopathy

Occasional
- Intracranial / cerebral / meningeal hemorrhage


Hereditary cerebral cavernous malformation

(no data available)